Revolutionary Antifouling Nanocoating

FUNBRUSH™ is a leading-edge nanocoating for biosensors and bioanalytical platforms, engineered for real-world performance in diagnostics, security, food safety, and environmental monitoring.

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Pioneering On-site Rapid Diagnostics in Complex Biofluids

Pushing the Frontiers in Biosensors

Our technology delivers outstanding antifouling and antibacterial protection, enabling sensitive analysis in even the most complex sample media.

Key Features

Outstanding antifouling and antibacterial performance, even in complex media
Easy post-functionalization with biomolecules or cells
No interference from the sample matrix
Compatible with diverse substrates and sensor platforms (SPR, QCM, optical fiber, electrochemical, and more)
Ultra-stable and reusable, even in harsh environments
Scalable for industrial and research needs

Application Highlights

Biosensors & Diagnostics

Monitoring biomolecular interactions in native conditions, detection of targets in real-world media such as unprocessed blood plasma
Healthcare

Rapid detection of chronic and infectious disease biomarkers, bacteria or viruses in body fluids
Food Safety

Detecting bacterial pathogens directly in food and water using portable biosensors.
Security

Detection of biological threats in complex media.
Microbiology and Cellular Research

Cytocompatible cell-on-chip platform reducing non-specific interferences
Environmental Monitoring

Field-ready, portable biosensors for water and environmental samples
Drug Delivery & Theranostics

Enabling new approaches in precision medicine
Imaging & Biochip Platforms

Broad compatibility with diverse sensing and imaging platforms

Transforming Biosensor Performance

FUNBRUSH™ empowers biosensors with the ability to function reliably in harsh environments, including undiluted biological fluids and raw food samples. Our coating drastically reduces non-specific adsorption and sample interference.

Key Advantages

Ultra-low fouling for superior sensor accuracy
Easy biomolecule or cell functionalization
Extreme stability and reusability
Compatible with diverse substrates and sensing platforms
Scalable synthesis by custom-made microfluidics stack reactor

Scientific Validation

FUNBRUSH™ is validated by rigorous testing and research.

Proven to reduce non-specific fouling from undiluted human plasma by ~95%
Demonstrated sensitive detection of SARS-CoV-2 in crude clinical and environmental samples
Portable multichannel QCM device with FUNBRUSH enables reliable detection of E. coli O157:H7 or S. aureus within 30 minutes, even in unprocessed foods

The Story Behind FUNBRUSH™’s Creation

FUNBRUSH™ was developed in direct response to the scientific community’s demand for ultra-reliable biosensors capable of operating in challenging real-world matrices.

Founded by Dr. Hana Lísalová and her team at the FZU - Institute of Physics of the Czech Academy of Sciences, FUNBRUSH™ represents years of research and innovation in antifouling polymer brush technologies and their biosensing applications. Field applications and rapid diagnostics have shaped its evolution.

FUNBRUSH™ Team